South Park is untouchable in this case. Personally i don't mind the racial content, Cartoons are meant to be funny and subjecting it to race don't offend anyone. You see a funny looking Caucasian running around with a gun and making a fool of himself with either a western cowbow accent or some bald guy with a speech impediment and it's ok. But then you have a funny looking asian (which is a rather amusing change from the average white guy) and all of a sudden it's bad.
I would image there are people that would complain about it though. Why would they take out Speedy Gonzalis though ? Did he offend the white or something ? lol or was he too Latino ?
You don't see 2D that well animated these days might i add.